Pilot gene expression analysis of inflamed synovium
نویسندگان
چکیده
منابع مشابه
Differential expression of syndecans and glypicans in chronically inflamed synovium
BACKGROUND Membrane-bound heparan sulphate proteoglycans (HSPGs) act as co-receptors and presenters of cytokines and are involved in cell-matrix and cell-cell adhesion. AIM To investigate which HSPGs are expressed in knee joint synovia from patients with different forms of arthritis and normal individuals. METHODS Synovial samples were obtained from patients with early rheumatoid arthritis ...
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OBJECTIVE To determine the utility of intercellular adhesion molecule (ICAM)-1 antibody-conjugated gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA-anti-ICAM-1) as a targeted contrast agent for the molecular magnetic resonance imaging (MRI) in collagen-induced arthritis (CIA). MATERIALS AND METHODS THREE GROUPS OF MICE WERE USED: non-arthritic normal, CIA mice in both the early inflamma...
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متن کاملDifferential binding of chemokines to macrophages and neutrophils in the human inflamed synovium
In chronic inflammatory foci, such as the rheumatoid joint, there is enhanced recruitment of phagocytes from the blood into the tissues. Chemokines are strongly implicated in directing the migration of these cells, although little is known regarding the chemokine receptors that could mediate their chemotaxis into the joint tissue. Therefore the objective of the study was to identify chemokine b...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 2012
ISSN: 0003-4967,1468-2060
DOI: 10.1136/annrheumdis-2011-201239.14